Skin — efficacy & protocols
Medical-aesthetic exosome preparations for the face — barrier repair, hydration, brightening, whitening, anti-aging and acne-mark recovery, with clear onset timelines and usage guidance.
As MYS-Exo’s advanced engineered achievement in the facial field, our MYS-Exo skin products use 3D directional-loading technology to reach top-level enrichment of the key signals for skin repair. Through molecular modification of both the regenerative and anti-inflammatory pathways, they focus on calming facial micro-environment fluctuations at the cellular source and accelerating tissue restructuring — a professional-grade engineered solution for deep aging and a compromised barrier.
- Inflammation Noise-Reduction (Anti-Inflammatory Engineering): Directionally boosting the exosome payload of endogenous inhibitory factors to precisely block the inflammatory signaling cascade, building a quiet, stable, healthy foundation and improving skin tolerance and self-repair.
- Source-Driven Regeneration (Regenerative Engineering): High-payload enrichment of key regenerative factors directly activates the endogenous repair instructions of fibroblasts and basal cells, accelerating collagen reconstruction and extracellular-matrix renewal.
- Barrier Reconstruction (Structural Engineering): Leveraging the transmembrane delivery of engineered exosomes to strengthen the dermal-epidermal junction (DEJ), improving epidermal tightness and water-locking and reshaping refined, firm skin with rapid downtime conversion.
Skin Barrier Repair
Repair damaged skin barrier, soothe redness, itching and inflammation, strengthen skin tolerance, ideal for sensitive skin and post-procedure care
Relieve stinging, itching and redness immediately
Redness and irritation fade, skin gets stable
Skin barrier fully recovered, less prone to sensitivity
How to use: Use twice daily. Avoid alcohol, acid and irritating ingredients when applying.
Targeting principle & mechanism
Anti-acne & anti-inflammatory
Core functional proteins: IL-10, TGF-β3, HSP70, lactoferrin, SOD, PDGF, IL-4
Targets: Inflamed acne sebaceous glands, macrophages, red swollen pustular areas
- Inhibits the NF-κB pathway and down-regulates pro-inflammatory factors for rapid de-reddening and de-swelling.
- Drives macrophages from pro-inflammatory M1 to reparative M2, breaking the inflammation cycle.
- Suppresses C. acnes proliferation and unclogs blocked sebaceous glands.
- Clears inflammatory free radicals, easing burning and stinging.
Soothing & sensitivity repair
Core functional proteins: IL-10, TGF-β, HSP90, E-cadherin, profilaggrin
Targets: Sensitive damaged keratinocytes, immune cells, barrier-broken areas
- Down-regulates inflammatory signalling at skin nerve endings, lowering sensitivity and easing itching, burning and redness.
- Suppresses over-active immune responses, improving steroid-damaged skin, post-acid stinging and seasonal redness.
- Heat-shock proteins stabilise cell membranes, reducing damage from external irritants.
Skin-barrier reconstruction
Core functional proteins: EGF, bFGF, TGF-β, filaggrin, loricrin, ceramide synthase, HAS
Targets: Keratinocytes, broken brick-and-mortar sites of the stratum corneum
- Activates keratinocyte proliferation and differentiation, speeding complete stratum-corneum regeneration.
- Up-regulates filaggrin and loricrin and boosts ceramide and cholesterol synthesis to seal intercellular gaps.
- Activates HAS to produce hyaluronic acid, locking moisture in and reducing trans-epidermal water loss.
- Long-term structural-protein supply improves recurrent sensitivity, peeling and poor moisture retention.
Deep Hydration & Softening
Balance oil and moisture, boost skin water-locking capacity, soften rough skin and relieve flakiness
Skin becomes soft, dry and tight feeling disappears
Long-lasting hydration, no more flakiness
Skin stays moisturized and smooth, superficial dry lines fade
How to use: Use twice daily. Combine with moisturizer for better results in dry environment.
Targeting principle & mechanism
Core functional proteins: bFGF, VEGF, HAS1/2/3, aquaporin AQP3, TGF-β
Targets: Keratinocytes, dermal fibroblasts, dermal microcirculation
- Up-regulates keratinocyte AQP3 water channels, improving the epidermis’s ability to draw in external moisture.
- Stimulates fibroblasts to secrete high-molecular-weight hyaluronic acid, filling dermal gaps for deep water storage.
- VEGF improves dermal microcirculation and the skin’s own water cycle, easing oily-but-dehydrated skin, flaking and dry lines.
Brightening & Even Tone
Accelerate skin metabolism, reduce pigmentation, brighten dull and sallow skin, even out skin tone
Sallowness and fatigue dullness fade
Skin tone becomes more uniform
Skin gains natural radiance
How to use: Preferably use at night. **Must apply sunscreen in daytime**.
Targeting principle & mechanism
Core functional proteins: HGF, SOD, GSH (glutathione), TGF-β, tyrosinase-inhibiting protein, TRP-1-inhibiting peptide
Targets: Melanocytes, keratin-metabolising cells, dull / pigmented areas
- Directly inhibits tyrosinase and TRP-1 activity, blocking melanin synthesis.
- Clears UV / oxidative free radicals to prevent new melanin and improve sallow dullness.
- Speeds orderly keratinocyte turnover to shed melanin-laden dead cells for an even, clear complexion.
- Inhibits melanin transfer to the stratum corneum, fading post-inflammatory marks, sun spots and uneven tone.
Whitening & Radiance
Exosomes inhibit melanin production, block pigment transfer and accelerate skin metabolism. It gently fades dark tone, sallowness and sun tan, brightens skin from the inside without irritation or peeling
Skin looks less sallow, clearer and brighter
Melanin fades, sun tan and dull patches lighten
Skin tone becomes even, fairer and luminous
How to use: Best used at night. Daily sunscreen is mandatory to avoid pigment rebound. Avoid harsh peeling ingredients.
Targeting principle & mechanism
Core functional proteins: HGF, SOD, GSH (glutathione), TGF-β, tyrosinase-inhibiting protein, TRP-1-inhibiting peptide
Targets: Melanocytes, keratin-metabolising cells, dull / pigmented areas
- Directly inhibits tyrosinase and TRP-1 activity, blocking melanin synthesis.
- Clears UV / oxidative free radicals to prevent new melanin and improve sallow dullness.
- Speeds orderly keratinocyte turnover to shed melanin-laden dead cells for an even, clear complexion.
- Inhibits melanin transfer to the stratum corneum, fading post-inflammatory marks, sun spots and uneven tone.
Anti-Aging, Firming & Line Smoothing
Stimulate collagen and elastin production, lift sagging skin, reduce fine lines and wrinkles
Skin feels firmer, superficial dry lines soften
Fine lines fade, facial contour gets lifted
Skin elasticity improves significantly, aging slows down
How to use: Use consistently for long-term anti-aging effect. Apply on face and neck, reinforce on wrinkle areas.
Targeting principle & mechanism
Core functional proteins: TGF-β1/3, bFGF, VEGF, HGF, elastin, procollagen, MMP-1 inhibitors, HSP70
Targets: Dermal fibroblasts, elastic-fibre cells, photo-aged / aging areas
- Activates the TGF-β/Smad pathway to continuously generate collagen, elastin and fibronectin, thickening the dermis and firming sagging.
- Inhibits MMP-1 collagenase, reducing collagen loss and slowing skin laxity.
- VEGF boosts dermal blood supply, improving dullness from late nights, dry lines and static fine lines.
- Antioxidant repair of UV-induced cellular DNA damage, slowing photo-aging.
- Rebuilds the dermal–epidermal junction (DEJ), softening nasolabial folds, eye-area fine lines and laxity creases.
Acne Marks & Pit Repair
Speed up wound repair, fade red & dark acne marks, smooth shallow acne pits
New red acne marks fade rapidly
Dark marks lighten, skin texture gets smoother
Old marks and shallow pits are greatly improved
How to use: Spot apply on acne marks. Keep sun protection to avoid pigment rebound.
Targeting principle & mechanism
Red acne-mark repair
Core functional proteins: TGF-β3, VEGF, IL-10
Targets: Dermal capillaries, macrophages, inflamed red-mark areas
- Inhibits abnormal capillary proliferation, fading vascular dilation and redness.
- Clears residual inflammation, preventing red marks turning dark.
- Speeds local tissue repair, fading fresh red marks.
Dark acne-mark repair
Core functional proteins: HGF, SOD, GSH (glutathione), tyrosinase-inhibiting protein
Targets: Melanocytes, pigment-deposit areas
- Inhibits tyrosinase activity, blocking further melanin synthesis.
- Clears oxidative free radicals, preventing pigment deepening.
- Speeds turnover of melanin-laden keratinocytes, fading deposited dark marks.
Atrophic acne-scar repair
Core functional proteins: bFGF, TGF-β1, PDGF, type I/III procollagen, fibronectin, MMP inhibitors
Targets: Dermal fibroblasts, collagen-broken / deficient areas
- Activates abundant fibroblast proliferation to synthesise type I/III collagen and elastin.
- Secretes fibronectin to build the dermal ECM scaffold, filling depressions.
- Inhibits MMP metalloproteinases to prevent loss of new collagen.
- Balances TGF-β1/3 to avoid over-proliferation and hypertrophic scarring.
How exosomes target the skin
Core functional proteins: CD9 / CD63 / CD81 tetraspanins, integrins, ICAM adhesion proteins, chemokine receptor CXCR4
Targets: Full-thickness damaged / problem skin areas and their target cells
- Targeted recognition: the exosome membrane carries a molecular “postal code” that binds matching ligands on cells in the problem area, actively grabbing the lesion while barely retaining on healthy skin.
- Transdermal delivery: the 30–150 nm nanoscale matches stratum-corneum gaps; with its phospholipid bilayer it enters cells intact via both passive penetration and active endocytosis, without being broken down.
- Intracellular release: once inside the cell the membrane fuses and ruptures, releasing functional proteins that directly regulate cell genes and signalling pathways — improving skin from the root.