Hair & scalp — efficacy & protocols
Engineered scalp exosomes for anti-hair-loss and regrowth, scalp barrier and microenvironment care, oil balance, hair strengthening, scalp anti-aging and post-treatment repair.
As the first engineered follicle-regeneration solution in the MYS-Exo family, our MYS-Exo scalp exosome products use 3D suspension directional-induction technology to precisely enrich the signalling molecules involved in follicle repair. Through “engineered payload enhancement” of the core exosomes, they focus on regulating scalp micro-environment homeostasis and restarting the follicle growth cycle at the molecular level — providing clinical-grade scientific support for precise hair care.
- Environmental Homeostasis (Anti-Inflammatory Engineering): Engineered over-expression of anti-inflammatory factors precisely counters the scalp’s inflammatory micro-environment; by suppressing abnormal immune responses around the follicle and quieting signal “noise”, it builds a calm, healthy foundation for follicle growth.
- Signal Activation (Activation Engineering): Targeted delivery of high-concentration Wnt/β-catenin signalling proteins acts directly on dermal-papilla cells; by inducing the signalling cascade it shortens the follicle’s resting phase and accelerates entry into the growth phase, reactivating atrophic follicles and driving spontaneous regrowth of the hair shaft.
- Deep Empowerment (Nutritional Engineering): Engineered enrichment of nutritional factors cascades to activate the tyrosine-kinase pathway, building an efficient nutrient matrix; by promoting microvascular formation around the follicle it strengthens the blood-oxygen and nutrient supply chain, markedly improving follicle thickness and hair-retention strength.
Scalp Barrier Repair & Sensitivity Soothing
Exosomes repair the damaged scalp barrier, soothe redness, itching, stinging and inflammation, improve scalp sensitivity caused by over-cleaning or seasonal changes, and strengthen scalp resistance.
Relieve scalp stinging, itching and redness immediately
Redness and irritation fade, scalp becomes stable
Scalp barrier fully recovered, less prone to sensitivity
How to use: Use twice daily. Avoid alcohol, soap-based and irritating ingredients when applying.
Targeting principle & mechanism
Core functional proteins: IL-10, TGF-β3, EGF, filaggrin, loricrin, HSP70, lactoferrin, SOD
Targets: Damaged scalp keratinocytes, peri-follicular macrophages/immune cells, sebaceous epidermal cells
- IL-10 + TGF-β3 inhibit the NF-κB pathway, down-regulating the factors behind persistent scalp redness, itching and pain.
- Drive macrophages from pro-inflammatory M1 to reparative M2, breaking the chronic scalp-sensitivity cycle.
- EGF promotes keratinocyte proliferation and up-regulates filaggrin and loricrin to rebuild the scalp brick-and-mortar structure, reducing water loss.
- HSP70 stabilises cell membranes and SOD clears irritation-induced free radicals, easing stinging after acid peels or colouring/perming.
- Lactoferrin suppresses over-growth of harmful scalp microbes, reducing inflammatory dandruff.
Oil Control & Scalp Microenvironment Care
Exosomes regulate sebum secretion, balance scalp oil and moisture, improve oily scalp, odor and clogged follicles, and balance scalp flora to create a healthy scalp microenvironment.
Scalp oil secretion slows down, less greasy and flat
Scalp oil and moisture balanced, dandruff and oiliness reduced
Scalp microenvironment stable, hair stays fresh and voluminous
How to use: Apply daily on oily scalp, focus on greasy areas. Avoid over-cleaning.
Targeting principle & mechanism
Core functional proteins: TGF-β2, PDGF, antimicrobial peptides, glutathione (GSH), HAS, lipid-metabolism regulators
Targets: Scalp sebaceous cells, scalp keratinocytes, scalp microbial colonisation areas
- TGF-β2 down-regulates the sebaceous lipid-synthesis pathway, reducing triglyceride and sebum over-secretion for lasting oil control without over-drying.
- Natural antimicrobial peptides inhibit Malassezia over-growth, cutting oily dandruff at the source.
- GSH neutralises rancid free radicals from oil oxidation, improving scalp odour.
- HAS regulates scalp oil–water balance and boosts stratum-corneum water storage, improving an oily-but-dehydrated scalp.
- Rebuilds the scalp’s weakly-acidic microbiome and keeps beneficial flora stable, reducing recurrent oiliness and dandruff.
Follicle Activation & Anti-Hair-Loss
Exosomes penetrate into hair follicles, activate follicle stem cells, prolong the anagen phase, shorten the telogen phase, improve hair loss, receding hairline and thinning hair caused by follicle atrophy, and strengthen hair roots.
Hair fall and breakage reduced significantly
Follicle activity improved, new vellus hair grows at hairline and part
Hair volume increased obviously, hair loss problem improved long-term
How to use: Use consistently for long-term effect. Focus on thinning areas, massage scalp for better absorption. Avoid perming and excessive hair pulling.
Targeting principle & mechanism
Core functional proteins: Wnt3a/Wnt10b, bFGF, VEGF, PDGF, TGF-β1, DHT antagonists, BMP inhibitors, fibronectin, type I/III procollagen
Targets: Bulge-region follicle stem cells, dermal-papilla (DP) cells, peri-follicular dermal microvasculature, follicle interstitial fibroblasts
- Wnt-family proteins activate the core Wnt/β-catenin growth pathway and inhibit the dormancy factor Dkk1, waking resting follicle stem cells and pushing follicles from telogen into anagen.
- VEGF promotes peri-follicular microvascular regeneration, delivering oxygen and nutrients to the dermal papilla and reversing follicle miniaturisation.
- DHT antagonists block dihydrotestosterone damage to the dermal papilla, improving androgenetic hair loss.
- bFGF + PDGF promote dermal-papilla proliferation and synthesise collagen and fibronectin, thickening the follicle base so new hair grows thicker and stronger.
- Down-regulate chronic peri-follicular inflammation to prevent immune attack on follicles (improving alopecia areata) and prolong the growth phase.
Hair Strengthening & Quality Repair
Exosomes fill the gaps of hair cuticles, repair the damaged hair cortex, improve dry, frizzy, split ends, brittle and dull hair caused by perming, sun exposure and styling, and enhance hair strength, elasticity and shine.
Hair becomes smooth and soft, shine improved
Split ends and breakage reduced, hair less prone to tangling
Hair cuticles fully closed, cortex repaired, hair stays strong and shiny
How to use: Apply daily on the middle and ends of damaged hair. Avoid excessive application on scalp. Use more frequently after perming and dyeing.
Targeting principle & mechanism
Core functional proteins: Hydrolysed keratin, keratin cross-linking enzymes, TGF-β3, elastin, fibronectin, SOD, laminin
Targets: Open damaged cuticle, keratin-deficient cortex areas, hair-shaft medulla gaps
- Releases keratin and cross-linking enzymes to fill cortical protein voids and repair broken disulphide bonds, improving tensile toughness and reducing breakage and split ends.
- Laminin closes lifted cuticle scales, locking in internal moisture and improving dryness and frizz.
- Elastin rebuilds the hair-shaft support structure, improving fine, flat hair and adding volume.
- SOD clears oxidative damage from UV and hot air, slowing hair ageing and yellowing.
Scalp Anti-Aging & Rejuvenation
Exosomes activate scalp fibroblasts, boost collagen and elastin production, improve scalp sagging, aging, fine lines and dullness, delay follicle aging, and maintain scalp youthfulness.
Scalp dullness and roughness improved, becomes soft and elastic
Scalp sagging reduced, fine lines faded, firmness improved
Scalp collagen regenerated continuously, aging slowed down
How to use: Use consistently for long-term anti-aging effect. Massage scalp for better absorption. Protect scalp from UV exposure.
Targeting principle & mechanism
Core functional proteins: TGF-β1/3, bFGF, VEGF, MMP inhibitors, HSP70, collagen synthase, glutathione
Targets: Scalp dermal fibroblasts, the dermal–epidermal junction (DEJ), aged atrophic follicles, scalp melanocytes
- The TGF-β pathway drives fibroblasts to synthesise type I/III collagen and elastic fibres, thickening the dermis, firming a loose scalp and softening scalp dry lines.
- MMP inhibitors block collagen-degrading metalloproteinases, reducing dermal collagen loss and slowing scalp sagging.
- VEGF improves overall scalp microcirculation, easing sallowness, dullness and poor oxygenation.
- HSP70 repairs UV-induced cellular DNA damage and antioxidant action suppresses scalp pigment dullness.
- Simultaneously nourishes aging follicles, delaying premature atrophy and shedding to keep the scalp youthful.
Post-Procedure & Post-Color Scalp / Hair Repair
Exosomes quickly repair the damaged scalp barrier and hair structure after perming, dyeing or scalp minimally invasive surgery, soothe inflammation, redness and stinging, accelerate wound healing, and shorten the recovery period.
Relieve scalp stinging and burning after surgery/perm
Scalp redness and inflammation fade, wound heals quickly
Scalp barrier and hair structure fully recovered
How to use: Use immediately after surgery/perm, 2–3 times daily. Avoid any irritating products. Keep scalp away from water, high temperature and friction.
Targeting principle & mechanism
Core functional proteins: EGF, IL-10, TGF-β3, lactoferrin, keratin-repair peptides, HAS, glutathione, fibronectin
Targets: Chemically-burned scalp, post-procedure wound keratinocytes, severely damaged hair shafts, inflamed sebaceous glands
- EGF speeds healing of wounds and chemically-damaged keratin, shortening the redness-and-stinging period after bleaching/colouring.
- IL-10 quickly suppresses the intense inflammation from chemical irritation, calming and de-reddening.
- Keratin peptides deeply repair cortical protein lost to bleaching, repairing severe split ends and breakage.
- GSH neutralises the strong oxidative damage from peroxide and alkaline dye agents, preventing scalp yellowing and brittle, dry hair.
- Fibronectin builds a scalp-wound repair scaffold, reducing post-transplant redness, scabbing and irritation-induced shedding; HAS repairs the barrier and hair-shaft moisture-locking, easing post-colour dryness and itch.
How exosomes target the scalp & follicles
Core functional proteins: CD9 / CD63 / CD81 tetraspanins, integrins, ICAM adhesion proteins, chemokine receptor CXCR4
Targets: Full-thickness damaged / problem scalp and hair-follicle areas and their target cells
- Targeted recognition: the exosome membrane carries a molecular “postal code” that binds matching ligands on cells in the problem scalp / follicle area, actively grabbing the lesion while barely retaining on healthy scalp.
- Follicular & transdermal delivery: the 30–150 nm nanoscale matches the scalp stratum-corneum gaps and peri-follicular space; with its phospholipid bilayer it enters cells intact via both passive penetration and active endocytosis, without being broken down.
- Intracellular release: once inside the cell the membrane fuses and ruptures, releasing functional proteins that directly regulate cell genes and signalling pathways — reactivating follicles and repairing the scalp from the root.
